The effects of hydro-alcoholic extract of spinach on pituitary-gonadal axis in male mice | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.


The effects of hydro-alcoholic extract of spinach on pituitary-gonadal axis in male mice

Author(s): Fatemeh Matboo and Mehrdad Modaresi

Spinach (Spionacia oleracea L.) is from chenopodiaceae family.This plant has many medicinal effects which are the most important aspects. This plant is really important because of having antioxidants and the highest absorption potential among vegetables for oxygen radicals. 75 male mice weredividedrandomly in five groups including control, placebo, and three experimental groups (50, 100, and 200mg/kg of the extract). The extract was injected in peritoneum for 20 days. Normal saline was used for placebo group. At the end of period, blood samples were taken and testosterone, LH and FSH amounts were measured. Obtained data were analyzed using SPSS program and one way ANOVA. Results showed that FSH and LH amounts were increased by 200 mg/kg group.Testosterone was increased in 50 and 100mg/kg groups but not in 200 mg/kg group.On the whole, results showed dose dependent effect of spinach extract on pituitary-gonadal axis of male sex which can affect reproduction potential.


Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 25868

Der Pharma Chemica received 25868 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry