Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


The pH-metric Study of Acetyl Salicylic Acid Metal Complexes in Mixed Solvent Media

Author(s): Vijayarohini P, Kavitha G, Bangaru Sudarsan Alwar S

The stepwise stability constant values of Acetyl Salicylic Acid with Cu(II) and Zn(II) have been studied using pH measurements in 70% DMF- 30% water medium and 50% DMF-50% water. The values of proton- ligand stability constants and metal-ligand stability constants were calculated. The metal-ligand stability constant of binary complex was evaluated using Irving-Rossotti titration technique.


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