Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

The rapid synthesis of schiff-bases without solvent under microwave irradiation and their antimicrobial activity

Author(s): Sandeep Miglani, Monika Mishra and Pooja Chawla

Microwave assisted synthesis, a green chemistry approach, is now a days widely practiced in the synthetic laboratories. In the present work, some Schiff’s bases were synthesized using microwave irradiation. They were purified and characterized by means of spectral data and subsequently subjected to the in vitro antibacterial activity against few pathogenic strains of microbes. It was observed that meta-substituted compounds like 3d, 3e and 3f exhibited good activity against almost all the organisms used in the study.


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