Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

The synthesis of pyrazole derivative containing azo dye moiety

Author(s): Vijay V Dabholkar, Omprakash G. Yadav, Navnath B. Shinde, Mustaqeem Mohammed A.

New substituted pyrazoles were prepared from p-chlorobenzaldehyde, ethyl acetoacetate as starting materials through azo dye containing 1, 3-diketones as intermediates. The structures of the products were confirmed by IR, 1H, 13C NMR and elemental analysis. Representative samples were screened for their anti-microbial activity against Gram-negative bacteria, Gram-positive bacteria, Fungi and Yeast using disc diffusion method.