Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Toxicological Effects of Arsenic Exposure on Haematology of Fresh Water Fish Channa punctatus

Author(s): Deepak K Jha, Bipin B Mishra, Kumud R Thakur, Pranay K, Sayrav K, Vikash Kumar, Parmanand Verma, Parimal K Khan

The metalloid arsenic is a natural environmental contaminant to which humans are routinely exposed through water, food, air, and soil. The impact of arsenic exposure on the haematological parameters of Channa punctatus was estimated. The important toxic manifestations include marked decrease in the concentration of Hemoglobin (Hb), Hematocrit (Ht), Red Blood Cell count (RBC), White Blood Cell count (WBC) decreased whereas corpuscular indices like Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH) and Mean Corpuscular Hemoglobin Concentration (MCHC) changed significantly in dose dependent manner. The alteration in these parameters can be used as a rapid method to assess health of fish in the aquatic environment exposed to arsenic.