Tribulus terrestris is an annual plant in the caltrop family (Zygophyllaceae) widely distributed around the world, that is adapted to grow in dry climate locations in which few other plants can survive .While this plant has lots of properties, the aim of this study is to overview its therapeutic effects than its nutritive and industrial effects. This review article was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases from1994 to 2016.totally, of 100 found articles, 47 articles were included. The search terms were “Tribulus terrestris”, “therapeutic”, “pharmacological”, Various studies have shown that Tribulus terrestris Possess Antiinfertility, DiabetesHeart disease, Anti-inflammatory effects, Antibacterial activity, Liverdisease, Supplemental activity, Kidneydisease, Anti-oxidant properties, Anti-cancer, Aphrodisiac activity, Anti-stress Oxidative stress, Liver and kidney, Hyperplasia, Antioxidant and metal chelator activity and Hepatoprotective activity, Anti- Androgenic Activity, Supplemental Sport, Pro-sexual androgen enhancing effects, Aphrodisiac properties. Tribulus terrestris not likely to become an important alternative to standard medical therapies unless there are changes to the regulation, standardization, and funding for research of these products.
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