Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Triterpenes and a coumarin derivative from Kibatalia gitingensis (Elm.) Woodson

Author(s): Consolacion Y. Ragasa, Vincent Antonio S. Ng, Mariquit M. De Los Reyes, Emelina H. Mandia, Chien-Chang Shen

Chemical investigations of the dichloromethane extracts of Kibatalia gitingensis (Elm.) Woodson afforded ursolic acid (1), squalene (2), α-amyrin acetate (3) and lupeol acetate (4) from the leaves, while the twigs yielded 1-4 and 6-hydroxy-7-methoxycoumarin or isoscopoletin (5). The structures of 1 and 5 were elucidated by extensive 1D and 2D NMR spectroscopy, while 2-4 were identified by comparison of their 13C NMR data with those reported in the literature.


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