GET THE APP

Validation of Analysis Method ?±-Mangostin Compound on Skin Fruit Extract Kandis Acid (Garcinia iowar Rob. Ex Choisy) Method HPLC | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Validation of Analysis Method ?±-Mangostin Compound on Skin Fruit Extract Kandis Acid (Garcinia iowar Rob. Ex Choisy) Method HPLC

Author(s): Roslinda Rasyid, Fitra Fauziah, Rahmadonil Akbar

This study uses a method of High-Performance Liquid Chromatography (HPLC) for the analysis of α-mangosteen in the extract Kandis. Analyses were performed with a flow rate of 1 ml/min using Phenomenal C18 column (150 × 4.6 mm) detector used was a UV detector at a wavelength of 240.5 nm. The mobile phase used was acetonitrile: 0.1% phosphoric acid in the ratio (85: 15) v/v. The regression equation of the calibration curve with the concentration of 1, 3, 5, 7 and 9 mg/ml, y=66474x-4456 validation of methods of analysis have been qualified parameter validation analysis, the value of accuracy of 98.62%, 97.90%, 95, 75% precision with 1.27%, 0.7%, 0.3% linearity with correlation Toe Fien 0.9998, the Limit of Detection (LOD) and Limit of Quantification (LOQ) limits respectively 0.22 mg/ml and 0.73 mg/ml. Levels of acid α-mangosteen in lands gained 0.05%.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Recommended Conferences
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry