Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


An efficient, one-pot, solvent-free synthesis of 1- amidoalkyl-2-naphthols using uranylacetateas new recyclable catalysts

Author(s): Mahmood Kamali

Solvent free and one-potcondensation of an aldehyde , acetamide or benzamide, and 2-naphthol was perfor med to obtain the corresponding 1-amidoalkyl-2-naphthol. T he 1-amidoalkyl-2-naphtholswereproducedby using UO 2 (CH 3 COO) 2 ·2H 2 Oas a catalyst at 90 ° C in high yield. This method has several advantages , for example excellent products yields, short times reaction, ea sy work up and solvent free condition. Also, the ca talyst was recyclable for five consecutive runs.

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