Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


Facile Synthesis of m-Terphenyls by Ring Transformation of 2H-Pyran-2-ones

Author(s): Priyanka Kole, Samata Shetgaonkar, Fateh V Singh

An alternative approach for the synthesis of meta-terphenyls 3a-g functionalized with electron-withdrawing or -donating groups is described and illustrated by carbanion-induced ring transformation of 6-aryl-2H-pyran-2-ones 1a-g with propiophenone 2 in excellent yields.

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