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A Novel Route to the Synthesis of Acridine Derivatives and Assay of their Antiviral Activity | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

A Novel Route to the Synthesis of Acridine Derivatives and Assay of their Antiviral Activity

Author(s): Soniya Singh*, Yamini Pandey and V. K. Pandey

A simple and convenient procedure was adopted for the synthesis of N-(3-acridin-9-yl-4-chloro/hydroxy-phenyl-alkyl)-arylamides/imides starting from 5-(arylamido/imido-alkyl)-2-chloro/2-hydroxy benzoic acids. The compounds were obtained in the yields ranging from 40 to 45% and exhibited less pronounced antiviral activity.


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