Medicinal plants are a blessing to humans since they are being used to treat existing and emerging ailments, either directly or indirectly. However, the availability of such plants, as well as their characteristics, has an essential impact. Catharanthus roseus is a very important medicinal herb in this direction as availability and its property both are fortunate thing for humankind. It is an evergreen plant first originated from islands of Madagascar. The flowers may vary in color from pink to purple and leaves are arranged in opposite pairs. It produces nearly 130 alkaloids mainly ajmalcine, vinceine, resperine, vincristine, vinblastine and raubasin. It is known for its antitumor, anti-diabetic, anti-microbial, anti-oxidant and anti-mutagenic effects. It has high medicinal values which need to be explored extensively. The purpose of the current study is to document updated data about its traditional and modern uses.