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Analytical Determination of Imiquimod in Various Solvents by Uv Spectroscopical Technique | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Analytical Determination of Imiquimod in Various Solvents by Uv Spectroscopical Technique

Author(s): Bhupinder Kaur

UV spectrophotometric method is the promising method which is developed for the programmed approximation of Imiquimod in bulk drug and different delivery systems. The absorption maxima of drug is shown at 244 nm and molar absortivity of 1.5899 ×104 l/mol×cm. Drug completely obeyed Beer-Lambert’s law within the concentration range of 0-2.5μg/ml. Correlation coefficients (R2) was found to be 0.998, 0.999. 0.999 in 0.1N HCl, Phosphate buffer pH 6.8 and methanol respectively.


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