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Antibacterial activity of 1-(4-methyl sulfonylphenyl)-3-(1-phenyl-3-aryl-1Hpyrazol- 4-yl)-2- propen-1-ones and itâ??s derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Antibacterial activity of 1-(4-methyl sulfonylphenyl)-3-(1-phenyl-3-aryl-1Hpyrazol- 4-yl)-2- propen-1-ones and itâ??s derivatives

Author(s): J. J. Vora, Dharmesh M. Patel, Ketan C. Parmar, Bhavesh M. Patel, Sunil B. Vasava

Various chalcone derivatives of 1-(4-methyl sulfonylphenyl)-3-(1,3-diphenyl-1H-pyrazol-4-yl)-2-propen-1-one were synthesized by condensation of 1,3-diphenyl-1H-pyrazole-4-carbaldehyde and 4-methyl sulfonylphenyl acetophenone. Chalcone derivatives were characterized by FT-IR, 1H-NMR, Mass spectral analysis and elemental analysis. All the synthesized compounds have been screened for their antibacterial activities by using cup-plate method.


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