Chemical Composition and Liver Protection of the Methanol Extract of Fortunella margarita (Lour.) Swingle Leaves | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X


süperbetin giriş

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

agariookey oyna istanbul okey


Chemical Composition and Liver Protection of the Methanol Extract of Fortunella margarita (Lour.) Swingle Leaves

Author(s): Magdy MD Mohammed, Nabaweya A Ibrahim, Seham S El-Hawary, Sanaa A Ali, Maha Z Rizk, Eman AW El-Abd

Liquid chromatography-mass spectrometric (LC/MS) analysis of the leave’s methanol extract of Fortunella margarita (Lour.) Swingle led to the identification without isolation of four main compounds. Extensive chromatographic purification revealed the isolation of acacetin 7-neohesperidoside, acacetin 7-rutinoside and 4-(β-D-glucopyranosyloxy) benzoic acid. Proton Nuclear Magnetic Resonance (1H-NMR) and Carbon-13 Nuclear Magnetic resonance (13C-NMR) along with HR-ESI/MS were used to elucidate the chemical structure of the isolated compounds. Liver protection against DMN and/or CCl4-induced toxicity was evaluated for the ME of F. margarita, and the obtained results showed that the ME decreased the elevated liver enzymes to the normal level, indicating the protection of structural integrity of hepatocytic cell membrane or regeneration of damaged liver cells.

Full-Text PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Recommended Conferences
Google Scholar citation report
Citations : 11575

Der Pharma Chemica received 11575 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons

rokettube brazzers

Turkish dental care is known to be affordable compared to other countries. If you want an affordible dentist Turkey, check out periodonta. It is heavily recommended for dental patients visiting Turkey