Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
Development and Validation of a Simple and Rapid UV Spectrophotometeric Method for Linagliptin in Bulk and Marketed Dosage Form
Author(s): Amruta Dalal*, Dr.Varsha Tegeli and Rajashri WaghmodeA simple, rapid, accurate and precise UV spectrophotometric Method for Linagliptin in Bulk and marketed tablet dosage form has been developed. The λmax of Linagliptin was found to be 295 nm. The method was linear in the range of 2-10 μg/ml presenting a good correlation coefficient (R2 = 0.9991). Method is validated as per ICH guideline and statistically significant as all the statistical parameters are within the acceptance range (%RSD ? 2.0 and SD ? 2. 0) for both Accuracy and precision.
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Citations : 25868
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