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Facile Synthesis of m-Terphenyls by Ring Transformation of 2H-Pyran-2-ones | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Facile Synthesis of m-Terphenyls by Ring Transformation of 2H-Pyran-2-ones

Author(s): Priyanka Kole, Samata Shetgaonkar and Fateh V Singh*

An alternative approach for the synthesis of meta-terphenyls 3a-g functionalized with electron-withdrawing or -donating groups is described and illustrated by carbanion-induced ring transformation of 6-aryl-2H-pyran-2-ones 1a-g with propiophenone 2 in excellent yields.


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