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Formulation and Characterization of Silver Nanoparticles Using Casiatora and Evaluation of Antimicrobial and Antioxidant Activities. | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Formulation and Characterization of Silver Nanoparticles Using Casiatora and Evaluation of Antimicrobial and Antioxidant Activities.

Author(s): Manoj Bali* and Shalu Shukla

Nanoparticles synthesis and application is broad, active and growing field of research. Nanoparticles have wide variety of novel applications depending on their size, shape, and composition. However, current production techniques are complex and/or may involve hazardous compounds. Using plant metabolites for nanoparticle synthesishas numerous advantages over conventional chemical, physical and biological methods. Silver nanoparticles (AgNPs) have attracted a lot of attention because of their use inpurification and quality management of air, biosensing, imaging and drug delivery system. In the present studies seed extract of cassia tora seeds has been employed for successful green synthesis of AgNPs from cationic silver. The physical properties size shape and morphology of synthesized nanoparticles were investigated by UV visible spectroscopy, fourier transform infrared spectroscopy, scanning electron spectroscopy and Zeta potential analysis. The antibacterial activity of biosynthesized AgNPs was studied against selected bacterial species Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Staphylococcus epidermidis and Escherichia coli. Antioxidant activity was checked using diphenylpicrylhydrazyl scavenging essay. The synthesized AgNPs exhibit great activity against selected bacteria along with the antioxidant activity.


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