Formulation, Characterization and In-Vitro Evaluation of Herbal Sunscreen Cream Containing Anthocyanins | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Formulation, Characterization and In-Vitro Evaluation of Herbal Sunscreen Cream Containing Anthocyanins

Author(s): Praveenkumar V Vijapur, Laxman S Vijapur*, Anita R Desai, Madhushree, Sushmita V Mudalagi, Apoorva P Daddenavar, Laxmi M Hatti and Venkatesh Kustagi

Herbal sunscreen cream containing anthocyanins extract of Punica granatum L and Brassica oleracea were successfully formulated and characterized. Anthocyanins were extracted from the Punica granatum L & Brassica oleracea L by maceration technique using 1% HCl (v/v) in methanol as a solvent. Anthocyanins cream were formulated using stearic acid, liquid paraffin, glycerin, cetyl alcohol, propyl paraben, propylene glycol, tri-ethanolamine, and distilled water. All the Anthocyanins cream formulations were evaluated for visual appearance and homogencity, pH, viscosity, spreadability, extrudability, centrifuge and in-vitro evaluation of sun protection factor was determined & formulations were evaluated for pH of which were about 6.6-6.9 within the range of skin pH. All the formulations were found to be homogeneous and there were no aggregate formation, there were no observable sediment in centrifuge tests. All the cream formulations showed good viscosity and they were capable to remain in the site of application for prolonged time. The values of spreadability indicated that the cream was easily spreadable by small amount of shear. All the cream formulations showed good extrudability. Among these formulations F2 showed excellent extrudability. In-vitro sun protection factor of F3 formulation showed enhanced protection against UV radiation as compared to F1 & F2.

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