The second virial coefficient, B 2 was measured using the gas filling and handling ap paratus made up of the gas sample and evacuation cylinders. After the experime nt the compressibility factor of CO 2 was evaluated to be 0.268. The deviation from unity is an indication that CO 2 at 373k and 19.6 atm behaves non-ideally. From lit erature however, the compressibility factor of CO 2 at this temperature is 0.274, showing an error of 2.1%. This error is within allowable limit. Subsequently the second vir ial coefficient was deduced to be -73.2 as compared with the value of -72.2 contained in literature. In all, the results obtained are plausible, precise and reason ably accurate.