Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

Plant Extract Mediated AgNps Synthesis in Averrhoa bilimbi and Syzygium cumini Leaf Extract, their Characterization and Antioxidant Potential Assessment

Author(s): Vijay D Mendhulkar, Sopan N Kharat, Snehal R Mahadik

The approach of green synthesis of silver nanoparticles was focused in the present work using leaf extract of two medicinal plants, Averrhoa bilimbi L. and Syzygium cumini L. in different intensities of sunlight. The method is light sensitive, simple, eco-friendly and quick for the synthesis of AgNPs from leaf extracts. These plants extract mediated SNP’s were comparatively characterized and evaluated for their antioxidant properties independently. The synthesized AgNPs were characterized by UV-spectroscopy, Nanoparticle Tracking Analysis (NTA), X-ray Diffraction (XRD), Transmission Electron Microscopy (TEM) and Fourier Transformed Infrared spectrum (FTIR) analysis. The UV-spectra showed maximum absorbance at 430 nm, NTA analysis shows 20 nm average sizes of AgNPs synthesized in A. bilimbi and 50 nm size in S. cumini leaf extract respectively. XRD analysis showed four Bragg’s reflection planes of the metallic silver in the 2θ range of 30º-80º and indexed as (111), (200), (220) and (311). TEM analysis revealed spherical shape of synthesized AgNPs in both the samples with similar diameter as recorded in NTA analysis. FTIR spectra indicates characteristic of the hydroxyl functional group in alcohols and phenolic compounds. The radical scavenging activity of silver nanoparticle was evaluated using DPPH assay. AgNPs samples of A. bilimbi and S. cumini showed notable scavenging potential indicating the ability of plant extract mediated AgNPs as a free radical scavenger.


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