Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

Screening Anti-Acne Potency of Microalgae: Antibacterial and Antioxidant Activities

Author(s): Erismar Amri, Abdi Dharma, Armaini, Djong Hon Tjong

Sixteen microalgae isolates were screened for their potency as the sources of anti-acne agents. The methanol and hexane extract of the isolates were assayed for their antibacterial bioactivity against Propionibacterium acnes and Staphylococcus aureus and theirantioxidant activities as free-radical-scavenging bioactivity by the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) test. The results showed that the extract of Micractinium sp. Ehime was the most potential as the source of anti-acnes agent based on their combined activities: antibacterial against P. acnes (clear zone 28.6 mm) and antioxidant activity (IC50 361.23 μg/ml).


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