Synthesis and Antitumor Evaluation of Some 5-fluorouracil Derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X


süperbetin giriş

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

agariookey oyna istanbul okey


Synthesis and Antitumor Evaluation of Some 5-fluorouracil Derivatives

Author(s): Mohammad Abdul Amir Ulaiwy, Mohammed Kamil Hadi, Muthanna Saadi Farhan, Alaa Radhi Khudhair

The present work is designed to synthesize some new derivatives of 5-Fluorouracil (5-FU) and evaluation of their antitumor activity in comparison with the reference drug 5-FU. A series of five 5-FU derivatives (1-5) were synthesized. Characterization of all compounds was done by elemental analysis (C, H and N), Fourier Transform Infrared (FTIR) spectroscopy and other physicochemical properties. All the newly synthesized compounds were tested for their in vitro antitumor activity; two cell lines were used for the evaluation, Human Cervix Carcinoma Cell Line (HeLa) and Human Breast Carcinoma Cell Line (AMJ13).


rokettube brazzers

agar io

wormax io

Elektronik Sigara