GET THE APP

Synthesis and Characterization of Novel Chalcones of 3-Benzylidene-2-chlorocyclohex-1-enecarbaldehyde as Potential Anti-proliferative Agents | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis and Characterization of Novel Chalcones of 3-Benzylidene-2-chlorocyclohex-1-enecarbaldehyde as Potential Anti-proliferative Agents

Author(s): Kathiravan PR, Muthukumaran S, Dhatchanamoorthy N, Prince AAM, Venugopal M

A series of novel chalcones of 3-Benzylidene-2-chlorocyclohex-1-enecarbaldehyde were synthesized by reacting benzylidene derivative of chloro aldehyde with different aromatic and heterocyclic ketones. All the synthesized compounds were characterized by 1H-NMR, 13C-NMR, IR and Mass spectra. The synthesized compounds were evaluated for their in vitro cytotoxicity. In particular, the compounds of the series 5 and fluorinated compounds of 5-9 exhibited superior cytotoxic property.


Full-Text PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry