Synthesis and Spectral Studies of Some Novel 9-Benzylpurine Derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X


süperbetin giriş

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

agariookey oyna istanbul okey


Synthesis and Spectral Studies of Some Novel 9-Benzylpurine Derivatives

Author(s): Arvinder Pal Singh* and Noolvi MN

Preparation of 9-benzylpurine derivatives is a tough task to any synthetic chemist. 2, 6-dichloropurine is firstly prepared for synthesizing novel 9-benzylpurine derivatives. This dihalopurine can be prepared from both Xanthine and Adenine and their comparison w.r.t percentage yield, purity was done. This prepared dihalopurine was benzylated and two isomers having N-Benzylation at 9- and 7-position of dihalopurine was reported. These formed two isomers were separated by column chromatography. After separation, we have synthesized 6-(2-furyl)-9benzylpurine by Stile Coupling reaction. Then, 6-(2-furyl)-9-benzylpurine was aminated to form novel 9-benzylpurine derivatives. The synthesized novel compounds were identified initially by TLC by marking spots of intermediate compound and final formed product on TLC plate using solvent CHCl3: Me OH (8.5:1.5). Then, their further characterization was done by I.R, 1HNMR, 13CNMR and Mass Spectral data.

Full-Text PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Recommended Conferences
Google Scholar citation report
Citations : 11575

Der Pharma Chemica received 11575 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons

rokettube brazzers

Turkish dental care is known to be affordable compared to other countries. If you want an affordible dentist Turkey, check out periodonta. It is heavily recommended for dental patients visiting Turkey