GET THE APP

Synthesis, Molecular Docking Analysis of New Hetercyclic Scaffolds-Based Quionoline Moiety as Possible Antimicrobial Agents | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis, Molecular Docking Analysis of New Hetercyclic Scaffolds-Based Quionoline Moiety as Possible Antimicrobial Agents

Author(s): Shruti Hirekurubar and Sanjeev kumar Giri*

In the present work, a general approach for the synthesis of new heterocyclic scaffolds-based quinoline were synthesized. In addition, molecules docking studies were achieved which showed that all the newly synthesized compounds are interacting with active site region of the target enzyme Thymidylate kinase -4QGG, DNA gyrase (PDB ID: 2XCT) Topoisomerase, Dihydrofolate reductase-DHFR- 2w9s, Clumping factor A (ClfA)-1N67 hydrogen bonds and pi-stacked interactions.


Full-Text PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 15261

Der Pharma Chemica received 15261 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry