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Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

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Farideh Mofazzeli

Department of Chemistry, Quchan Branch, Islamic Azad University, Quchan, Iran

Publications

  • Research Article   
    Spectrometric Determination of Amitriptyline in Real Samples after Separation by Two Liquid-phase Microextraction Method
    Author(s): Farideh Mofazzeli

    The main aim of this research is using the preconcentration and sample preparation method, based on directly suspended drop microextraction method of amitriptyline prior to UV-vis spectrophotometer. Here, the target compound was extracted from an aqueous sample solution (donor phase) into an organic solvent drop (acceptor phase), which was suspended in the sample solution without using a microsyringe needle as a supporting device. Several important parameters which influence the extraction efficiency such as the kind of extracting solvent, extraction time, volumes of the sample solution and organic extraction solvent, stirring rate, pH of the donor phase and salt effect were investigated. Under the optimal conditions the enrichment factor was 25. By plotting absorbance versus concentration of the analyte in the standard solutions, calibration curve was obt.. Read More»

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