Khaliq UZ Zaman Khan

Department of Chemistry University of Kashmir Srinagar, Jammu and Kashmir, India

Publications

• Review Article   
  Structure: Mechanistic Studies and Pharmacological Importance of Oxadiazole Derivatives and Allied Oxygen Heterocycles
  Author(s): Noor UD Din Zargar* and Khaliq UZ Zaman Khan
  
  Oxadiazole is a five-membered heterocyclic compound containing two carbon, two nitrogen, and one oxygen atom in the ring. 1,3,4-oxadiazole is widely investigated because of its significant interacting potential with distinct binding sites in the biological systems.A range of 2-substituted phenyl -1, 3, 4-oxadiazole-2- thion derivatives(2) of pharmacological interest have been synthesisized from substituted carboxylic acids (1). Pyridine carboxylic acids (3) have also been transformed to 5-pyridyl-1, 3, 4-oxadiazole-2-thion derivatives (4) in excellent yields. ?-lactones are oxygen containing heterocycles extensively distributed in nature and display a broad spectrum of biological activities.Avariety of gama lactones have been generated from epoxides and esters .Oxygen heterocycles of the type (6) possessing antitumor properties have been obtained from alkenyl ketones in high yields. M.. Read More»
  

  Abstract PDF