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Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Maedeh Dahaghin

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Publications

  • Method   
    UV spectrophotometric method development and validation for the quantitative measurement of Rosmarinic acid
    Author(s): Ali Rahmani* and Maedeh Dahaghin

    The main aim of the current research was development and validation of simple, accurate UV spectrophometric method for measurement of Rosmarinic acid (RA). Method validation parameters including linearity, precision, specificity, accuracy, and limit of detection (LOD), limit of quantification (LOQ) were established. 327 nm was found to be the maximum wavelength of RA in solution. Calibration curve illustrated a linear correlation between the absorbance and concentration in the range of 1-14 μg/ml with a correlation coefficient (r2) of 0.9987. ICH guideline was studied for the linearity, accuracy, precision, LOD and LOQ. The method may be efficient for the determination of RA in liposomes and requires inexpensive instrument... Read More»
    DOI: 10.4172/0975-413X.15.3.1-4

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