Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X


süperbetin giriş

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

agariookey oyna istanbul okey

Mahmoud NM Yousif

Photochemistry Department, Chemical Industries Research Division, National Research Centre, Cairo, Egypt


  • Research Article   
    Synthesis and Biological Activity of Cycloocta[b]pyridine Derivatives
    Author(s): Mahmoud NM Yousif* and Nabil M. Yousif

    Cyclooctanone reacts with arylidene malononitrile to afford cycloocta[b]pyridine-3-carbonitrile derivatives 2a-b. 2-Amino-4-(4-chlorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile 2a reacts with benzoyl chloride and acetic anhydride to afford compounds 3 and 4 respectively. N-(4-(4-Chlorophenyl)-3-cyano-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-yl)benzamide 3 and N-(4-(4-Chlorophenyl)-3-cyano-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-yl)acetamide 4 reacts with hydrazine hydrate to afford compounds 5a,b. 5-(4-Chlorophenyl)-4-imino-2-phenyl-6,7,8,9,10,11-hexahydrocycloocta[5,6]pyrido[2,3-d]pyrimidin-3(4H)-amine 5a and 5-(4-Chlorophenyl)-4-imino-2-methyl-6,7,8,9,10,11-hexahydrocycloocta[5,6]pyrido[2,3-d]pyrimidin-3(4H)-amine 5b reacts with D-glucose and D-ribose to produce compounds 6a-d. Compounds 6a,b react with acetic anhydride to afford acetylated derivative 7a.. Read More»

    Abstract HTML PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Recommended Conferences
Google Scholar citation report
Citations : 11575

Der Pharma Chemica received 11575 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons

rokettube brazzers

Turkish dental care is known to be affordable compared to other countries. If you want an affordible dentist Turkey, check out periodonta. It is heavily recommended for dental patients visiting Turkey