GET THE APP

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Mehrdad Modaresi

Department of Animal Science, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran

Publications

  • Research Article   
    Comparing the Effects of Cannabis and Paroxetine on Depressive Symptoms by Using Forced Swimming Test in Mice
    Author(s): Samaneh Ebrahimi, Mehrdad Modaresi* and Ilnaz Sajjadian

    Current study was carried out to compare the effects of cannabis and paroxetine on laboratory depressive symptoms of mice using forced swimming test. Sixty female mice from weight range of 25-30 were divided into 6 groups. Depression was enforced by injecting tetrabenazine. Hydroalcoholic extract of cannabis was injected intraperitoneal in 50, 100 and 200 mg/kg of weight, paroxetine was injected in ¼ mg/kg dose for paroxetine group and control group did not receive any thing to evaluate depression. Forced swimming test was used and increased movement time (in seconds) or reduced immobility time were used as depression indices. Multivariate covariance analysis showed that 50 and 100 mg/kg doses increased movement time and decreased immobility time in proportion to control and paroxetine significantly, which indicates depression reduction. Therefore, .. Read More»

    Abstract HTML PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry