Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Nto Johnson Nto
Department of Anatomy, Faculty of Basic Medical Sciences, College of Medicine, University of Nigeria Enugu Campus, NigeriaPublications
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Research Article
Phytochemical Composition and Acute Oral Toxicity Study of Ethanolic Extract of Root of Plumbago Zeylanica
Author(s): Nto Johnson Nto, Chike I Patrick Anibeze, Elizabeth Finbarrs-Bello, Emmanuel Anayochukwu Esom* and Uloaku Akubueze Nto-Ezimah
The phytochemical composition of a plant gives an impression of its medicinal property. Plumbago Zeylanica (Pz) is one of the medicinal plants in sub-Saharan Africa consumed as a supplement for maintaining good health and as an aphrodisiac for enhancing sexual vigor. There is paucity of data on the phytochemical screening and the acute Oral toxicity of root of Plumbago zeylanica harvested in Africa. This study evaluated the bioactive compounds and the acute Oral toxicity of ethanolic root extract of Pz. Phytochemical screening was done using standard and the acute Oral toxicity was conducted and computed using the improved Up-and-Down (UPD) method of Organization for Economic corporation and Development test guideline 425 statistical program which provides a point estimate of LD50. Phytochemical analysis revealed high phenolic and steroid.. Read More»