Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Otaigbe JOE

Department of Pure and Industrial Chemistry, University of Port Harcourt, Nigeria

Publications

  • Research Article   
    Isolation and Characterization of Microcrystalline Cellulose from Papaya Stem
    Author(s): Nwajiobi CC*, Otaigbe JOE and Oriji O

    Microcrystalline cellulose (MCC) was isolated from papaya stem, characterized and compared with a commercial brand MCC. The dried pulverized papaya stem was subjected to alkaline treatment using aqueous NaOH and NaOCl solutions. Alpha cellulose obtained was modified by partial hydrolysis using 2.5 M HCl at boiling temperature to produce microcrystalline cellulose. The Physicochemical properties such as bulk, tapped and true densities, degree of polymerization, particle sizes, moisture content, angle of repose etc were examined and compared with a commercial brand sample (C-MCC). Results have shown that the percentage yields of alpha cellulose and CU-MCC obtained from the starting dried stem material were 23.78 and 20.70, respectively. Fourier Transform Infrared (FT-IR) spectra of CU-MCC and C-MCC confirmed the presence of OH and (C=O) carbonyl function.. Read More»

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