GET THE APP

Description and Synthesis of Benzylidene Compound

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Short Communication - Der Pharma Chemica ( 2023) Volume 15, Issue 4

Description and Synthesis of Benzylidene Compound

Swamy Nath*
 
Department of Chemistry, University of Technology, Lucknow, Uttar Pradesh, India
 
*Corresponding Author:
Swamy Nath, Department of Chemistry, University of Technology, Lucknow, Uttar Pradesh, India, Email: saminath@edu.in

Received: 03-Apr-2023, Manuscript No. dpc-23-97542; Editor assigned: 05-Apr-2023, Pre QC No. dpc-23-97542; Reviewed: 19-Apr-2023, QC No. dpc-23-97542; Revised: 21-Apr-2023, Manuscript No. dpc-23-97542; Published: 28-Apr-2023, DOI: 10.4172/0975-413X.15.4.48-49

Abstract

Benzylidene is not a specific compound, but rather a functional group that can be found in various organic molecules. The benzylidene functional group is a carbon-carbon double bond (C=C) that is attached to a benzene ring. In this answer, I will describe the general synthesis and characterization of compounds containing a benzylidene functional group. Synthesis of Benzylidene Compounds: Benzylidene compounds can be synthesized using a variety of methods, but one common approach involves the condensation of an aldehyde or ketone with an aromatic compound that contains a reactive hydrogen atom. The reaction is typically catalyzed by an acid or base, and the resulting product is an imine, which can be hydrolyzed to yield the corresponding benzylidene compound.

Keywords

Benzylidene; Functional group

INTRODUCTION

Characterization of Benzylidene Compounds: Benzylidene compounds can be characterized using a range of techniques, including: Infrared (IR) Spectroscopy: IR spectroscopy can be used to detect the C=C double bond in the benzylidene functional group. The stretching frequency of this bond typically appears in the range of 1600-1680 cm^-1. Nuclear Magnetic Resonance (NMR) Spectroscopy: NMR spectroscopy can provide information about the chemical environment surrounding the benzylidene functional group. The chemical shift of the C=C double bond typically appears in the range of 6.0-7.5 ppm. Mass Spectrometry (MS): MS can be used to determine the molecular weight and fragmentation pattern of the benzylidene compound. Elemental Analysis: Elemental analysis can be used to determine the empirical formula of the benzylidene compound.

In summary, benzylidene compounds can be synthesized by condensing an aldehyde or ketone with an aromatic compound containing a reactive hydrogen atom, followed by hydrolysis of the resulting imine. These compounds can be characterized using techniques such as IR spectroscopy, NMR spectroscopy, MS, and elemental analysis. X-Ray Crystallography: X-ray crystallography can be used to determine the three-dimensional structure of the benzylidene compound in the solid state. UV-Vis Spectroscopy: UV-Vis spectroscopy can be used to analyze the electronic absorption properties of the benzylidene compound, particularly the conjugated system of the C=C double bond. Differential Scanning Calorimetry (DSC): DSC can be used to determine the melting point and thermal stability of the benzylidene compound. Thermo gravimetric Analysis (TGA): TGA can be used to analyze the thermal decomposition behavior of the benzylidene compound. Overall, a combination of these techniques can provide comprehensive characterization of benzylidene compounds, allowing for a detailed understanding of their chemical and physical properties.

Gas Chromatography (GC): GC can be used to separate and analyze the individual components of a mixture containing the benzylidene compound. High-Performance Liquid Chromatography (HPLC): HPLC can also be used to separate and analyze the individual components of a mixture containing the benzylidene compound, particularly for compounds that are not volatile enough to be analyzed by GC. Elemental Mapping:

Elemental mapping can be used to determine the distribution of elements within a sample containing the benzylidene compound, providing insight into its spatial distribution and potential applications in materials science. Surface Analysis Techniques: Surface analysis techniques, such as X-ray photoelectron spectroscopy (XPS) and scanning probe microscopy (SPM), can be used to analyze the surface chemistry and topography of the benzylidene compound, particularly in applications related to thin films and surface coatings [1-5].

DISCUSSION

These techniques can provide valuable information about the structure, properties, and behavior of benzylidene compounds, both in isolation and in complex mixtures or environments. This information can be used to optimize synthesis and processing methods, characterize the performance of the compounds in various applications, and guide the development of new materials and technologies. Electrochemical Analysis: Electrochemical analysis techniques, such as cyclic voltammetry and chronoamperometry, can be used to study the redox properties of the benzylidene compound, which can provide insights into its behavior in electrochemical applications, such as energy storage and conversion devices. Spectroscopic Ellipsometry: Spectroscopic ellipsometry can be used to analyze the optical properties of thin films containing the benzylidene compound, such as their refractive index and thickness, providing valuable information for applications such as sensors and optical coatings. Dynamic Light Scattering: Dynamic light scattering can be used to measure the size and distribution of particles or aggregates containing the benzylidene compound, providing insights into its behavior in solution and in applications such as drug delivery and nanotechnology.

Rheology: Rheology can be used to measure the mechanical properties of materials containing the benzylidene compound, such as their viscosity and elasticity, providing insights into their flow behavior and potential applications in areas such as coatings, adhesives, and composites. In summary, there are a wide variety of analytical techniques that can be used to characterize benzylidene compounds, each providing unique insights into their structure, properties, and behavior. These techniques can be applied across a range of fields, including materials science, organic chemistry, and biotechnology, and can be used to optimize synthesis methods, characterize the performance of the compounds in various applications, and guide the development of new materials and technologies. Nuclear Magnetic Resonance Spectroscopy (NMR): NMR spectroscopy is a powerful analytical technique that can be used to study the molecular structure and dynamics of benzylidene compounds. By analyzing the behavior of nuclei in a magnetic field, NMR can provide information about the chemical environment, stereochemistry, and conformational properties of the compound. Mass Spectrometry (MS): MS can be used to analyze the molecular weight, structure, and fragmentation patterns of the benzylidene compound, providing information about its chemical identity and purity [6-10].

CONCLUSION

Infrared Spectroscopy (IR): IR spectroscopy can be used to analyze the vibrational modes of the benzylidene compound, providing information about the functional groups present and allowing for identification and characterization of the compound. Circular Dichroism Spectroscopy (CD): CD spectroscopy can be used to study the chiral properties of the benzylidene compound, providing information about its optical activity and enantiomeric purity.Solid-State Nuclear Magnetic Resonance Spectroscopy (ssNMR): ssNMR spectroscopy can be used to study the structure and dynamics of the benzylidene compound in the solid state, providing information about its packing and intermolecular interactions. These analytical techniques, along with others not listed, can provide valuable information about the chemical and physical properties of benzylidene compounds, which can be used to optimize their synthesis and processing, as well as to guide their use in various applications.

REFERENCES

  1. Brijesh KP, Anjani KP, Abhay PS, et al., Der Pharmacia Lettre. 2015, 7(1): p. 113-117
  2. Google Scholar

  3. Anjani KP, Brijesh KP. J CONDENSED MATTER. 2011, 13: p.12-23.
  4. PandeyA BK. Pandey K, Singh CK. Int J Modern Physics: Conference Series. 2013, 22: p. 24-27.
  5. Google Scholar, Crossref

  6. Anjani KP, Harendra KR. 2014, 4: p. 195-201.
  7. Jalal SK, Al-Sheikh AM, Al-Saqa RH. Iran J Sci Technol Trans Sci. 2001, 45: p. 391-396.
  8. Google Scholar, Crossref

  9. SKJalal. International Journal of Thermodynamics. 2020, 23,,p,  245-250,
  10. Google Scholar   

  11. Angel RJ, Miozzi F, Alvaro M. Minerals. 2019, 9: p. 562.
  12. Google Scholar     Cross Ref

  13. AL-Saqa RH, AL-Taie SJ. J Siberian Federal University. Mathematics & Physics. 2019, 12: p. 371-378.
  14. M.AL-sheikh A, AL-Saqa RH. Global Proceedings Repository, American Research Foundation.
  15. Stacey FD. Geophysical J Int. 2000, 143: p. 621-628.

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 25868

Der Pharma Chemica received 25868 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry