A green and efficient synthesis of biscoumarin derivatives is achieved in aqueous media catalyzed by tamarind juice as a natural catalyst. This Knoevenageal condensation is achieved using 4-hydroxycoumarin and different aromatic aldehyde in aqueous media at reflux condition. The present protocol avoids the use of hazardous reagents and toxic solvents. One-pot condensation, shorter reaction times, high yields, operational simplicity, simple workup procedure are some of the additional features of this protocol.
Select your language of interest to view the total content in your interested language