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Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Aishwarya Hiremath

Department of Pharmaceutics, Rajiv Gandhi University of Health Sciences, Karnataka, India

Publications

  • Research Article   
    An Overview and in vitro Evaluation of Effervescent Tablets of Lornoxicam with Antacids
    Author(s): Aishwarya Hiremath*

    Objective: The objective of this study was to mask the bitterness of lornoxicam by inclusion complex method using β cyclodextrin (β CD), to prepare lornoxicam effervescent tablets with antacids by wet granulation method using citric acid, tartaric acid with sodium bicarbonate as effervescent mixture, which is useful to neutralize the acid that may be occurred due to the co-administration of lornoxicam and to compare the in vitro drug release and Acid Neutralizing Capacity (ANC) of tablets of optimized batch with marketed products. Methods: Authentication of lornoxicam was done by FTIR and DSC analysis. The spectral interference of the excipients at analytical wavelength of lornoxicam was studied using UV method. Prepared tablets of lornoxicam then subjected to evaluation of post compression parameters such as thickness and diameter.. Read More»

    Abstract PDF