Ghislain Kende

Laboratory of Medicinal Chemistry and Pharmacotechnie of Medicinal Plants, CHIRED-CONGO 81, Dahomey Street Poto-Poto,Brazzaville B.P. 13.922, Republic of the Congo

Publications

Research Article
Larvicidal and ovicidal activities of some cinnamaldehyde derivatives Against Anopheles gambiae, malaria vector agent
Author(s): Victor N’goka, Guy Crépin Enoua, Tony Wheellyam Pouambeka, Ghislain Kende, Gelase Fredy Nsonde Ntandou, Ninon G.E.R. Etsatsala* and Ouamba Jean-Maurille

This study presents the research studies conducted on vector control for the fight against malaria, a very devastating disease with a high rate of mortality and morbidity in sub-Saharan Africa. Following an ethnobotanical, ethnopharmacological, chemical analysis, larvicidal and ovicidal activities of essential oils as well as their main chemical constituents; eleven compounds including related derivatives have been either purchased or synthesized and evaluated for their larvicidal and ovicidal activities. Cinnamaldehyde and o-Nitrocinnamaldehyde exhibited the highest activity withLC50 = 55 mg /L following by Citral (LC50 = 64 mg /L), Cinnamic acid (LC50 = 65 mg /L), and Thymol (L50 = 67 mg /L), against larvaes. Furthermore, Citral, and Cinnamaldhyde showed the highest activity against eegs, with LC50 = 0,015 and 0.020 respectively. This study revealed that the compounds were more acti.. Read More»
DOI: 10.4172/0975-413X.14.11.25-33

Abstract HTML PDF