Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Vijayalakshmi R

Department of Pharmaceutical Analysis, GIET School of Pharmacy, Rajahmundry-533296, Andhra Pradesh, India


  • Research   
    Spectrometric Estimation of Gliclazide, Nortriptyline, Cilnidipine in Pure and Tablet Dosage Form Using MBTH
    Author(s): Vijayalakshmi R*, Chamundeswari RN, Surya Kumari R and Suhasini S

    The objective of the present work is to develop simple, precise and accurate colorimetric methods for the estimation of Gliclazide (Method A), Nortriptyline (Method B), Cilnidipine (Method C) using MBTH (3-Methyl-2-Benzothiaazide Hydrazine) reagent. All the three Methods were developed on Perkin Elmer LAMBDA 25 UV/VIS spectrophotometer with 1cm quartz cells. Quantification of Gliclazide, Nortriptyline, Cilnidipine were done by Oxidative coupling method using MBTH as reagent. Gliclazide (Method A), Nortriptyline (Method B) and Cilnidipine (Method C) undergoes oxidation with ferric chloride and couples with MBTH. The coupled oxidant shows maximum absorbance measured at 660 nm for Gliclazide (Method A), 650 nm for Nortriptyline (Method B), and 600 nm for Cilnidipine (Method C). The colorimetric method was extensively validated as per ICH guidelines and all the parameters were within the .. Read More»

    Abstract HTML PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 25868

Der Pharma Chemica received 25868 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry