Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Ebuka Leonard Onyeyilim

Department of Pure and Industrial Chemistry University of Nigeria, Nsukka, Nigeria


  • Research Article   
    Author(s): Vivian Ifeoma Okonkwo, Chinedu Emmanuel Nnadi, Cosmas Chinweike Eze, Faith Elijah Temitope and Ebuka Leonard Onyeyilim*

    Plasmodium berghei is transmitted by Anopheles mosquitoes and it infects the liver after being injected into the bloodstream by a bite of an infected female mosquito. We have reported the synthesis of benzothiazole derivatives (compound 3a-b) by condensing 2-aminothiophenol with different aromatic aldehydes in polyethylene glycol-400 and the progress of the reaction was monitored using thin-layer chromatography, with dichloromethane and n-hexane used as a developing solvent in the ratio of 2:1. The synthesized compound was characterized by 13C-Nuclear Magnetic Resonance and 1H- Nuclear Magnetic Resonance. The acute toxicity of the synthesized compound was evaluated and found to be less toxic. The antimalarial activity of the compound was also studied in-vitro using albino mice and the result showed that the compound has significant antimalarial activity against Plasmodium berghei... Read More»
    DOI: 10.4172/0975-413X.15.4.54-63

    Abstract HTML PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 25868

Der Pharma Chemica received 25868 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry