Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X


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Osama IG Khreit

Department of Pharmacology, Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Omar Almukhtar University, Elbeida City, Libya


  • Research Article   
    A Comparative Study of Physical and Chemical Parameters of Selected Paracetamol Tablets Available in the Pharma Market of Libya
    Author(s): Osama IG Khreit, Hanan AM Alkailani and Wala SK Alqathafi

    Quality of any pharmaceutical product is very important because drugs must be marketed as safe and therapeutically active formulations whose performance is consistent and predictable. Evaluation of the physiochemical properties of the pharmaceutical products can ensure their quality as well as bioavailability and impart optimum therapeutic activity. Paracetamol tablet was chosen for this comparative study because it is widely used worldwide for treating moderate to severe pain and fever. In this present study was compared the weight variation, hardness and assessment of state content of ten brands of paracetamol tablets marketed in Libya following USP/BP guidelines. All ten brands of paracetamol tested conformed to the USP/BP weight variation test. All the brands had average hardness of ≥79 N, which was satisfactory for immediate release of tablet like .. Read More»

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