Sribhadram Abhishek

Department of Pharmaceutics, Sri Sivani College of Pharmacy andhra Pradesh, India

Publications

• Research Article   
  Anti Covid Drug Nanoparticles in the Formulation Controlled Release Dosage Form
  Author(s): Sribhadram Abhishek*
  
  Favipiravir belongs to Biopharmaceutics Classification System Class I drug that has higher solubility and higher permeability. The drug needs to be administered frequently (2-3 times a day) total 1800 mg drug /day and also have shorter half-life it means the drug is eliminating from the body in 2-4.5 hrs. The present study was to overcome the half-life of favipiravir. So, it is formulated into nano-particles were prepared using a hydrophobic polymer-ethyl cellulose by modified solvent evaporation technique. Optimized formulation was selected and prepared into a tablet formulations using different excipients which control the drug release. The favipiravir loaded nanoparticles were sent to (FT-IR) studies and it shown the absence of interactions of drug with other excipients and also other studies like DSC, SEM. At the end of the 10th hour, F1-F6 formulations released 84.71%-96.43% of t.. Read More»
  

  Abstract PDF