Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Srikanth Kanithi

Department of Sciences and Humanities, Chemistry Division, Vignan’s Foundation for Science, Technology & Research, Vadlamudi, Guntur, Andhra Pradesh-522 213, India


  • Research Article   
    Reversed Phase-UPLC Separation Analysis of Amitriptyline and Pregabalin from Their Degradants
    Author(s): Srikanth Kanithi and Naga Sesha Sai Pavan Kumar Chebolu*

    A simple, expeditious, and explicit stability-indicating Ultra Performance Liquid Chromatography (UPLC) analytical method was developed and validated for the quantitative analysis of Amitriptyline and Pregabalin in bulk drugs and combined dosage formulations. The method was validated by using Acquity UPLC HSS C18 (100 mm × 1.8 μ) column, the column temperature was maintained at 25°C and the run time 3 min. The mobile phase was a mixture of Mobile Phase: A–Acetonitrile, B–0.1% Ortho Phosphoric acid in water, injection volume of samples was 1 μl and the UV detection λmax at 256 nm. The retention times were discerned as 1.76, 2.11 min and the linearity range was covered from 2.5 μg/ml to 15 μg/ml, 18.75 μg/ml to 112.5 μg/ml of Amitriptyline and Pregabalin respectively. The validation of the method established as .. Read More»

    Abstract HTML PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry